MethodologyCommitteeon ch. 3
Your evidence is mostly observational. How do you rule out that the microbiome only changes after autoimmunity has begun?
Answer outline
- Cohorts such as TEDDY sample the microbiome from three months of age, before seroconversion.
- That narrows down reverse causation but does not rule it out.
- Chapter 3 names this as a limitation of the thesis.
AAcurio
Unsupported
The source classifies stages of presymptomatic type 1 diabetes but does not define primary prevention. Add a suitable source or revise the claim.